
Akkermansia
A single-strain probiotic with live Akkermansia muciniphila to support gut lining integrity and digestive health.*

Your Foundational Probiotic for a Stronger Gut

A single-strain probiotic with live Akkermansia muciniphila to support gut lining integrity and digestive health.*

Founded by PhD doctors and scientists from Johns Hopkins, Harvard, Berkeley, and Stanford
Created Glucose Control, the only medical probiotic on the market clinically shown to improve A1C in type 2 diabetes
Featuring strains you can't get anywhere else, including live Akkermansia, a keystone strain that's been in 3,000+ scientific
publications
We continue to drive microbiome research forward through our own rigorous research and partnerships in clinical trials
Next-generation anaerobic strains are manufactured in our own strict, oxygen-free facility in the U.S.

Leading Functional Medicine, Epigenetics & Longevity Expert & Educator
New Frontiers Clinic

Extend Podcast Host, “Longevity Doctor of the Year”
Next Health Clinic

Bestselling Author & Weight Loss Expert
17 Day Diet

Professor of Genomics, Physiology, & Biophysics, Director
Weill Cornell Medicine, WorldQuant Initiative for Quantitative Prediction
Top doctors and health influencers are talking about Pendulum's cutting-edge science and life-changing products.
Learn more
Our first investor and continuing research partner. We are the first consumer microbiome company to co-develop a registry with the Mayo Clinic.

Our team has served as board members for ADA chapters and the ADA Research Foundation. Pendulum was profiled at the annual Scientific Sessions.
"I would describe Pendulum's approach as "rational" probiotic discovery based on prospectively matching microbial strains that can produce specific ligands known to modulate a known target for a particular issue."
"I was an early adopter of probiotics, and have used all the touted brands over the years. Nothing (!) brought me regularity until this one. I'd also been struggling with sugar cravings and weight gain; into my 2nd bottle, I literally awoke one day to find those cravings gone. Like, overnight. I'm feeling calmer and far more energetic - I'll take this product always!"
"The microbiome is a tantalizing and exciting new frontier. Pendulum is taking a rigorous and methodical science-based approach to developing these microbiome solutions."
"My gut health has improved 100%."
Your best line of defense
Stress, repeated antibiotic use, and other external factors can degrade the integrity of your gut lining. When this happens, the toxins in your gut can more easily infiltrate your body. Another adverse effect is a reduction in the amount of Akkermansia muciniphila, a naturally occurring bacterial strain essential for maintaining the integrity of your gut barrier and thus your overall gut health.


Pendulum Akkermansia reinforces the mucin layer of the gut lining*, reducing permeability* and supporting overall digestive comfort.
*Based on preclinical studies
**Based on a consumer survey of 172 people over 3 months
Pendulum Akkermansia supports your gut lining and may influence the gut-brain axis—the communication pathway that helps regulate hunger signals. A stronger gut lining can help rebalance the signals that affect cravings and appetite.
*Based on a consumer survey of 80 people over 3 months
How Akkermansia fortifies your gut
1- RESET
The Akkermansia bacteria feeds on mucin, the thin protective layer that keeps your gut lining strong and less permeable.
2 - REPLENISH
As the Akkermansia consumes mucin, it stimulates your gut to produce new mucin.
3 - REINFORCE
Freshly produced mucin fortifies your gut barrier and keeps toxins from traveling to the rest of your body.

"When I was trying to recover from the greatest health crisis of my life, Akkermansia muciniphila played a pivotal role. It’s crucial for optimizing gut barrier function and immune response."

Family Physician, Functional Medicine
About Akkermansia"Having the ability to replace Akkermansia and combining it with the right dietary factors has made an incredible difference in both my patients' metabolic and gut health."

Functional Registered Dietitian Nutritionist
About Akkermansia“So many of my clients have low levels of Akkermansia identified on their gut microbiome tests. Being able to provide the microbiome with what it specifically needs, coupled with lifestyle interventions, helps me optimize not only my client's gut but overall health and wellbeing.”

Nurse Practioner, Functional Medicine
About AkkermansiaIndividual results may vary. Reviews reflect individual experiences and do not represent health claims or guarantees.
As an adult, I've gotten more and more sensitive to eating certain foods, and how they would affect my digestion. Since taking Akkermansia, I've noticed a big difference and am able to eat more things without worrying about repercussions later. Would definitely recommend!
I have to say that I have tried several products but heard your podcast and was willing to try it. IMMEDIATELY after the first few doses, my tummy stopped rumbling after lunch, I noticed the bloating and gas I usually had was almost non existence. I have been on it for 3 months and I am borrowing my daughters last bottle so I don't run out on vacation. I am really impressed and so happy..I have recommended it to several people who are ready to reclaim their gut health.. Thanks again for helping me feel so much better..
I’ve been taking probiotics for years with no obvious results. Three-four weeks after starting to take this akkermansia my stomach is noticeably flatter (I hadn’t even realised I was bloated!) and my digestive system seems to have reset back to how it used to be 5-10 years ago before I started to have symptoms of leaky gut. Super impressed by this product.
I’ve struggled with gut issues for the last 20 years (following a surgery and massive dose of antibiotics). I have tried every supplement / diet possible (including treating leaky gut) and none made a material difference. I was so excited to try akkermansia and it did not disappoint. I’m about 6 weeks in and for the first time since I can remember my bloating and major issues are gone. I used to look pregnant by 4pm. Not anymore! Highly recommend!
I’ve been taking the daily probiotic and Akkermansia for approximately 90 days and have seen an incredible improvement in overall stomach issues. I’ve lived with issues most of my life and have finally found a supplement that seems to make a difference.
Are there studies that show that Akkermansia improves gut health?
Yes, there are studies suggesting that Akkermansia muciniphila, a species of bacteria found in the gut, improves gut health.
What consumer surveys have been done on Akkermansia?
In a consumer study of 172 people taking Akkermansia over 12 weeks of product use, 82% reported improved bowel movements, 77% reported improved GI/gut health, 71% reported reduced occasional gas & bloating, and 67% reported reduced diarrhea. In a separate consumer study of 86 people taking Akkermansia for 3 months, 91% reported reduced overall food cravings and 86% reported reduced sugar cravings.
How does Akkermansia compare to other Pendulum products, and which one is right for me?
Akkermansia is a single-strain probiotic, meaning it only contains the live Akkermansia muciniphila strain.
You might notice that our multi-strain probiotics also contain Akkermansia. That’s because we so deeply believe in the power and efficacy of this keystone strain for gut health that we use it in all of our formulations.
Which probiotic is right for you depends on your goals.
If you’re trying to improve your gut health → Akkermansia
Is Akkermansia safe?
Akkermansia contains Akkermansia muciniphila, a beneficial bacterial strain naturally found in the human gut of people with healthy microbiomes. Akkermansia muciniphila has undergone extensive safety studies and found to be safe.
Can or should I take Akkermansia if I’m pregnant?
Akkermansia contains a beneficial bacterial strain that exists within the gut microbiome of healthy people, including during pregnancy. To date, Akkermansia has not been studied in women who are either pregnant, planning to become pregnant, or breastfeeding. Please consult with your healthcare provider to see if this product may be a good fit for you.
Are there any side effects of taking Akkermansia?
When starting any new probiotic such as Akkermansia, there can be an adjustment period. You may experience some gastrointestinal symptoms (increased gas, bloating, nausea, or loose stools) that usually resolve over the initial 14 days or with discontinuation of the product. If you experience symptoms that are severe or do not resolve, please consult your healthcare provider.
How long should Akkermansia be taken?
Akkermansia is a daily supplement and can be taken for as long as you experience benefits.
Should someone lower their dose after taking for 60, 90, 180 days?
To maintain the benefits of Akkermansia, we do not recommend lowering the dose.
Can I travel with Akkermansia?
You can travel with Akkermansia. Just toss your bottle in your bag and once you reach your destination, put it in the fridge if possible. Refrigeration is best though not required.
What lifestyle habits should someone adjust to maximize the benefits of Akkermansia?
A diet filled with colorful fruits, vegetables, polyphenols, and a wide range of dietary fibers supports a healthy gut microbiome and will maximize the benefits of Akkermansia. It’s also important to maintain healthy stress levels and remain physically active.
Will the effects plateau after a certain amount of time?
Akkermansia is designed to improve your gut health and should continue supporting your gut microbiome for as long as you take the product.
We're confident you will love Pendulum Akkermansia, so we want you to try it risk-free. If you are dissatisfied with Akkermansia within 30 days of your first order delivery, contact us and we’ll issue you a full refund (minus shipping & handling).
Products purchased from our website(s) with a shipping address outside of the United States (and associated territories) are not eligible for refunds. Customers are solely responsible for any additional charges incurred for customs clearing and international duties or taxes.
Due to the nature of our products, they cannot be reused in any way once they leave our facility. In order to avoid waste, we do not accept returns.
*This policy is only available for orders within the USA.
We currently ship to the United States are limited to Akkermansia.